Apparatus, method, computer-readable medium, and use for therapy planning in treatment of a patient

US8315810B2 · kind B2 · utility

Assignee

• KONINKLIJKE PHILIPS ELECTRONICS NV · NL

Inventors

• Heinrich von Busch · Aachen, DE
• Bernd Schweizer · Herzogenrath, DE
• Jens-Christoph Georgi · Aachen, DE

Key dates

• Filing date: Nov 6, 2007
• Grant date: Nov 20, 2012
• Expiry date: Jul 23, 2029

Classification

• Technology area (CPC G): Physics
• CPC primary: G16H50/30
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

An apparatus, method, system, computer-readable medium and use for individual patient therapy planning of diseases such as cancer for different therapy modalities, such as radiation therapy and chemotherapy is provided. A new aspect of the invention is that the degree of bone marrow depression of the patient is related to the count of immature blood platelets, which are measured before each treatment. Some embodiments of the invention provide an advantage allowing reducing the level of uncertainty in the prediction of the risk of bone marrow depression, and thus enabling to safely improve the therapy effect by an increase of the radiation dosage and/or chemical dosage to the individual patient while the risk for bone marrow depression is minimized.