Droplet actuator loading and target concentration
US8317990B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Mar 24, 2008 |
| Grant date | Nov 27, 2012 |
| Priority date | — |
| Expiry date | May 29, 2029 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01L2400/0487
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A droplet actuator and method of providing a droplet comprising an target substance on the droplet actuator, and including discrete flow and continuous flow functionality. Discrete flow function is controlled by electrodes arranged for conducting droplet operations on a substrate surface. The continuous flow function includes a fluid path arranged for flowing a fluid therethrough. The discrete flow and continuous flow functions may be by a barrier, including a second fluid path through the barrier. The continuous flow function may include a capture surface comprising a component having an affinity for the target substance. Methods of the invention may include flowing a fluid comprising the target substance through the fluid path; capturing the target substance on the capture surface; and forming a droplet in the discrete flow region via the second fluid path and the electrodes comprising the captured target substance.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.