Synthetic peptides immuno-reactive with rheumatoid arthritis auto-antibodies
US8318440B2 · kind B2 · utility
1Cited by
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20Claims
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Key dates
| Filing date | Dec 3, 2008 |
| Grant date | Nov 27, 2012 |
| Priority date | — |
| Expiry date | Jul 7, 2029 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/102
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Embodiments of the present invention relate to a three dimensional matrix of selected, synthetic peptide mimic sequences that are preferentially recognized by auto-antibodies, specifically by autoimmune antibodies, to be detected in patients afflicted with rheumatic arthritis, enabling enhanced sensitivity and specificity in detection of these antibodies in pre-symptomatic patients, in patients showing symptoms as well as patients confirmed positive for rheumatoid arthritis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.