Immunomagnetic capture and imaging of biological targets
US8318445B2 · kind B2 · utility
5Cited by
13References
22Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 7, 2009 |
| Grant date | Nov 27, 2012 |
| Priority date | — |
| Expiry date | Apr 4, 2031 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/58
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention relates to methods and systems for labeling, isolating, detecting, and/or enumerating a statistically significant number of biological cells, or other biological analytes of interest, present in a complex matrix sample. The isolation of a biological target of interest from a sample mixture is done by immunomagnetic separation. Upon introduction of the sample within an imaging chamber, the capture complex (biological target-magnetic capture agent) will be attracted by the magnetic field and will lay on the surface of the chamber in the focal plane of the imaging system.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.