Compounds modifying apoptosis
US8318717B2 · kind B2 · utility
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3Claims
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Key dates
| Filing date | May 23, 2006 |
| Grant date | Nov 27, 2012 |
| Priority date | — |
| Expiry date | Nov 26, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07B2200/11
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to compounds capable of inhibiting binding of the Smac protein to Inhibitors of apoptosis (IAPs). Such compounds are preferably capable of inhibiting IAP and thus may promote apoptosis or sensitize cells for apoptosis. The compounds may be used in the treatment of proliferative diseases, such as cancer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.