Pyrazine compounds, their use and methods of preparation
US8318723B2 · kind B2 · utility
1Cited by
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10Claims
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Key dates
| Filing date | Aug 15, 2007 |
| Grant date | Nov 27, 2012 |
| Priority date | — |
| Expiry date | Apr 9, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D413/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides compounds according to formula (I)their use and methods for preparation wherein A, X, Y, R1, R2 and R3 are defined herein. The compounds of the invention inhibit specific serine/threonine kinases involved in inflammatory processes and aberrant cell proliferation, and are thus useful for treating associated diseases and pathological conditions such as Pim kinase-mediated diseases and pathological conditions involving inflammation, including Chron's disease, inflammatory bowel disease, rheumatoid arthritis, and chronic inflammatory disease, or aberrant cell proliferation including various cancers.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.