Patent · US Active

Crystalline forms of (6R)-L-erythro-tetrahydrobiopterin dihydrochloride

US8318745B2 · kind B2 · utility

12Cited by

4References

22Claims

0Family size

Assignee

MERCK & CIE · CH

Inventors

Rudolf Moser · Schaffhausen, CH
Viola Groehn · Dachsen, CH
Thomas Egger · Illnau, CH
Fritz Blatter · Reinach, CH

Key dates

Filing date	Dec 3, 2009
Grant date	Nov 27, 2012
Priority date	—
Expiry date	Dec 3, 2029

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P43/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Crystal forms of (6R)-L-erythro-tetrahydrobiopterin dihydrochloride, hydrates and solvates and processes for their preparation are provided. These crystal forms are either intermediates for the preparation of stable polymorphic form B or are suitable for solid formulations.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.