Methods for administering DPD inhibitors in combination with 5-FU and 5-FU prodrugs
US8318756B2 · kind B2 · utility
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4References
38Claims
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Key dates
| Filing date | Dec 5, 2005 |
| Grant date | Nov 27, 2012 |
| Priority date | — |
| Expiry date | Jan 23, 2026 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods for improved administration and dosing of DPD inhibitors in combination with 5-FU and/or 5-FU prodrugs are provided, comprising first administering to a patient in need thereof a DPD inhibitor that substantially eliminates activity of the enzyme and thereafter administering 5-FU or a 5-FU prodrug, wherein the level of 5-FU or 5-FU prodrug is in substantial excess of DPD inhibitor in the patient.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.