Antioxidant polymers containing [1,2]-dithiolane moieties and uses thereof
US8318795B2 · kind B2 · utility
8Cited by
28References
72Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 29, 2008 |
| Grant date | Nov 27, 2012 |
| Priority date | — |
| Expiry date | Jun 4, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08B37/003
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention describes polymers containing 1,2-dithiolanes capable of acting as scavengers of free radicals, metals and reactive oxygen species. Also described are methods of synthesizing the antioxidant 1,2-dithiolane derivatives and polymerization thereof to produce biodegradable antioxidant polymers. The antioxidant polymers of the present invention may be used to treat diseases or conditions caused by oxidative stress and other free radical mediated conditions. The antioxidant polymers may also be used for the preparation of antioxidant particulate delivery devices of therapeutic agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.