Patent · US Active

Naphthyridin-2 (1 H)-one compounds useful as antibacterials

US8318940B2 · kind B2 · utility

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18Claims
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Inventors

Key dates

Filing dateJan 15, 2010
Grant dateNov 27, 2012
Priority date
Expiry dateJan 15, 2030

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P31/06
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Compounds of Formula (I),wherein substituents R1, R2 and R5 are as defined, and Ar represents substituted phenyl, pyridyl, pyridazinyl, pyrimidinyl, pyrazinyl, thiazolyl, furanyl, imidazolyl and thiophenyl substituted by a hydroxyalkyl substituent and an optional other substituent; compositions containing them, their use in therapy, including their use as antibacterials, for example in the treatment of tuberculosis, and methods for the preparation of such compounds, are provided.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.