Process for preparing 2,4-dioxotetrahydrofuran-3-carboxylates
US8318955B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Aug 11, 2010 |
| Grant date | Nov 27, 2012 |
| Priority date | — |
| Expiry date | Jan 19, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D307/60
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Process for preparing 2,4-dioxotetrahydrofuran-3-carboxylates of the formula (I) and/or (I′)comprising the reaction of a haloacetyl chloride compound of the formula (II)with a malonic ester of the formula (III)in which Hal, R1 and R2 have the definitions stated in the application, in the presence of a suitable base and optionally in the presence of a solvent; the addition of a sufficient amount of water to the reaction mixture; and the isolation of the desired 2,4-dioxotetrahydrofuran-3-carboxylate.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.