Enhanced method for delivering bevacizumab (avastin) into a brain tumor using an implanted magnetic breather pump
US8323270B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Oct 19, 2009 |
| Grant date | Dec 4, 2012 |
| Priority date | — |
| Expiry date | Feb 21, 2031 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61M2210/0693
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A magnetically controlled pump is implanted into the brain of a patient and delivers a plurality of medicating agents mixed with Avastin at a controlled rate corresponding to the specific needs of the patient. The current invention comprises a flexible double walled pouch that is formed from two layers of polymer. The pouch is alternately expanded and contracting by magnetic solenoid. When contracted, the medicating agent Avastin is pushed out of the pouch through a plurality of needles. When the pouch is expanded, surrounding cerebral fluid is drawn into the space between the double walls of the pouch from which it is drawn through a catheter to an analyzer. In cases where a tumor resection is not performed, an intratumoral catheter will be implanted. Cerebral fluid drawn from the patient is analyzed. The operation of the apparatus and hence the treatment is remotely controlled based on these measurements and displayed through an external controller.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.