Systems, devices, and methods for optically clearing tissue
US8323273B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Aug 12, 2006 |
| Grant date | Dec 4, 2012 |
| Priority date | — |
| Expiry date | Feb 4, 2031 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61N2005/0649
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
Embodiments of the present disclosure provides systems, devices, and methods for non-invasively modifying, maintaining, or controlling local tissue optical properties. Methods and devices of the disclosure may be used for optically clearing tissue, for example, for diagnostic and/or therapeutic purposes. A method of optically clearing a tissue may comprise contacting the tissue with an optical clearing device having a base, an array of pins fixed to one side of the base, a brim fixed to the base, an inlet port in the base, an exit port in the base, and a handpiece interface tab fixed to the side of the base opposite the array of pins, applying a mechanical force to the tissue, and illuminating said tissue with at least one wavelength of light through the optical clearing device. A method may further comprise controlling the temperature of the tissue illuminated.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.