Patent · US Active

Antibodies that bind OV064 and methods of use therefor

US8323645B2 · kind B2 · utility

4Cited by

13References

9Claims

0Family size

Assignee

Millennium Pharmaceuticals, Inc. · US

Inventors

Ole Petter Veiby · Westborough, US
John Babcook · Vancouver, CA

Key dates

Filing date	Mar 10, 2006
Grant date	Dec 4, 2012
Priority date	—
Expiry date	Nov 11, 2027

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2317/92
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Antibodies and antigen-binding fragments of antibodies that bind OV064 are disclosed. The antibodies bind an extracellular domain of OV064. Some of the antibodies and antigen-binding fragments bind an epitope on OV064 sufficient to induce internalization. In some embodiments, the antibodies are humanized, chimeric or human. Nucleic acids and vectors encoding the antibodies or portions thereof, recombinant cells that contain the nucleic acids, and compositions comprising the antibodies or antigen-binding fragments are also disclosed. The invention also provides therapeutic and diagnostic methods utilizing the antibodies and antigen-binding fragments provided herein.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.