Polymer conjugate of taxane
US8323669B2 · kind B2 · utility
9Cited by
26References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 22, 2007 |
| Grant date | Dec 4, 2012 |
| Priority date | — |
| Expiry date | May 21, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08L2203/02
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
[Problems] To provide a novel taxane derivative which can release the medicinal substance in a bioenzyme-independent manner, is expected to have an effective therapeutic efficacy, and has a water-solubility.[Means for Solving Problems] Disclosed is a polymer conjugate of a taxane, which comprises a polymer having a polyethylene glycol moiety and two or more succinic acid monoamide moieties and a taxane, wherein a carboxylate group in the polymer and an alcoholic hydroxyl group in the taxane are bound to each other via an ester bonding.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.