Patent · US Active

Nanoparticles for immunotherapy

US8323696B2 · kind B2 · utility

32Cited by

9References

26Claims

0Family size

Assignee

ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) · CH

Inventors

Jeffrey A. Hubbell · Austin, US
Conlin P. O'Neil · Prilly, CH
Sai Reddy · Basel, CH
Melody Swartz · Chicago, US
Diana Velluto · Lausanne, CH
André van der Vlies · Zürich, CH
Eleonora Simeoni · Bottens, CH

Key dates

Filing date	Aug 29, 2008
Grant date	Dec 4, 2012
Priority date	—
Expiry date	Nov 11, 2030

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K2039/6093
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Nanoparticles that activate complement in the absence of biological molecules are described. The nanoparticles are shown to specifically target antigen presenting cells in specifically in lymph nodes, without the use of a biological molecule for targeting. These particles are useful vehicles for delivering immunotherapeutics. Surface chemistries and chemical formulations for the nanoparticles are described.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.