Patent · US Active

Hosts and fermentation processes for cellulase production

US8323931B2 · kind B2 · utility

1Cited by

1References

46Claims

0Family size

Assignee

Iogen Energy Corporation · CA

Inventors

Loreta Gudynaite-Savitch · Gatineau, CA
Christopher D. Hindle · Ottawa, CA
Theresa C. White · Ottawa, CA

Key dates

Filing date	Nov 3, 2009
Grant date	Dec 4, 2012
Priority date	—
Expiry date	Nov 1, 2030

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N1/38
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

A fermentation process for the production of cellulase mixtures is provided. The process comprises providing a genetically modified host filamentous fungus that overexpresses a Xyr1 transcription factor and/or that is partially or completely deficient in expressing one or more hemicellulase enzyme. The host filamentous fungus is cultured in a medium comprising a carbon source. The carbon source contains from about 60 wt % to about 100 wt % hemicellulose-derived carbohydrate and less than 5% of a cellulase-inducing carbohydrate or contains from about 25 wt % to about 100% wt % hemicellulose-derived sugar alcohol in combination with from about 0 wt % to about 75 wt % glucose, glycerol or a combination thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.