Patent · US Active

Process for the enantioselective enzymatic reduction of secodione derivatives

US8323936B2 · kind B2 · utility

0Cited by

8References

12Claims

0Family size

Assignee

IEP GMBH · US

Inventors

Antje Gupta · Wiesbaden, DE
Anke Tschentscher · Eltville am Rhein, DE
Maria Bobkova · Idstein, DE

Key dates

Filing date	Sep 7, 2011
Grant date	Dec 4, 2012
Priority date	—
Expiry date	Sep 7, 2031

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY02P20/55
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The invention relates to a process for the enantioselective enzymatic reduction of secodione derivatives. The secodione derivative is reduced with an oxidoreductase/dehydrogenase in the presence of NADH or NADPH as a cofactor. The secodione derivative is used in the reaction batch at a concentration of ≧10 g/l and the oxidized cofactor NAD or NADP formed by the oxidoreductase/dehydrogenase is regenerated continuously.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.