Surface comprising DNA polymerase having mutations bound through an affinity tag

US8323939B2 · kind B2 · utility

Assignee

• PACIFIC BIOSCIENCES OF CALIFORNIA, INC. · US

Inventors

• David Hanzel · Palo Alto, US
• Jonas Korlach · Camas, US
• Paul Peluso · East Palo Alto, US
• Geoffrey Otto · Brookline, US
• Thang Pham · Mountain View, US
• David R. Rank · Palo Alto, US
• Stephen Turner · Menlo Park, US

Key dates

• Filing date: Oct 26, 2007
• Grant date: Dec 4, 2012
• Expiry date: Apr 7, 2031

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2319/23
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

Active surface coupled polymerases, surfaces that include such polymerases, and methods of making and using surface-attached polymerases are provided.