Methods for inhibiting CLC-2 channel with GATX2
US8324158B2 · kind B2 · utility
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23References
7Claims
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Key dates
| Filing date | Jul 12, 2007 |
| Grant date | Dec 4, 2012 |
| Priority date | — |
| Expiry date | Jul 12, 2027 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P1/12
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compositions and methods of using scorpion venom peptide that is a ligand for ClC channels are provided. One aspect provides a pharmaceutical composition containing an amount of GaTx2 effective to inhibit ClC activity. Methods of treating a disorder or symptom of a disorder related to aberrant ClC channel activity are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.