Treatment of T-cell mediated diseases
US8324167B2 · kind B2 · utility
24Cited by
95References
3Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 18, 2010 |
| Grant date | Dec 4, 2012 |
| Priority date | — |
| Expiry date | Jul 14, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D241/08
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides a method of treating T-cell mediated diseases and a method of inhibiting the activation of T-cells using certain diketopiperazines. The invention also provides methods of synthesizing diketopiperazines and pharmaceutical compositions comprising certain diketopiperazines. The invention further provides methods of making improved pharmaceutical compositions of proteins and peptides by either increasing or decreasing the content of diketopiperazines in the compositions and the resultant improved pharmaceutical compositions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.