Fused thiophene derivatives as kinase inhibitors
US8324204B2 · kind B2 · utility
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Key dates
| Filing date | Jun 4, 2007 |
| Grant date | Dec 4, 2012 |
| Priority date | — |
| Expiry date | Jul 19, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D495/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A series of 5,6-dihydro-1-benzothiophen-7(4H)-one derivatives, and analogues thereof, which are substituted in the 2-position by an optionally substituted morpholin-4-yl moiety, being selective inhibitors of PI3 kinase enzymes, are accordingly of benefit in medicine, for example in the treatment of inflammatory, autoimmune, cardiovascular, neurodegenerative, metabolic, oncological, nociceptive or ophthalmic conditions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.