Cold menthol receptor antagonists

US8324217B2 · kind B2 · utility

Assignee

• Janssen Pharmaceuticals, Inc. · BE

Inventors

• Raymond W. Colburn · Spring House, US
• Scott L. Dax · Landenberg, US
• Christopher Flores · Lansdale, US
• Donald Ludovici · Quakertown, US
• Jay M. Matthews · Lansdale, US
• Mingde Xia · Spring House, US
• Xiaoqing Xu · Monmouth Junction, US
• Mark A. Youngman · Warminster, US
• Bin Zhu · Spring House, US

Key dates

• Filing date: Feb 6, 2012
• Grant date: Dec 4, 2012
• Expiry date: Feb 6, 2032

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D417/06
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds are represented by Formula I as follows:wherein A, B, L, Q, R1, R2, and R3 are defined herein.