Patent · US Active

Dual-specific IL-1α/IL-1β antibodies

US8324350B2 · kind B2 · utility

3Cited by

12References

92Claims

0Family size

Assignee

Abbott Laboratories · US

Inventors

Chung-Ming Hsieh · Newton, US
Bradford L. McRae · Northborough, US
Yuliya Kutskova · Northborough, US
John E. Memmott · Framingham, US
Michael Roguska · Cambridge, US
Ian Tomlinson · Stevenage, GB
Carrie Enever · Cambridge, GB
Steven Grant · Cambridge, GB
Mihriban Tuna · Cambridge, GB

Key dates

Filing date	Dec 28, 2007
Grant date	Dec 4, 2012
Priority date	—
Expiry date	Apr 13, 2030

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2317/92
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention provides an isolated, dual-specific antibody, or an antigen-binding portion thereof, which is specific for human IL-1α and human IL-1β. The dual specific antibodies of the invention also neutralize both human IL-1α and human IL-1β. The invention also provides domain antibodies (dAbs) specific for human IL-1α and human IL-1β.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.