Oxocarbonamide peptide nucleic acids and methods of using same
US8324359B1 · kind B1 · utility
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25Claims
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Assignee
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Key dates
| Filing date | Nov 29, 2007 |
| Grant date | Dec 4, 2012 |
| Priority date | — |
| Expiry date | Oct 4, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/003
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention concerns oxocarbonamide peptide nucleic acids (OxoPNAs). OxoPNAs provide increased stability, sensitivity, and specificity as compared to their natural DNA and RNA counterparts. The OxoPNA molecules of the present invention may be employed in a wide range of applications, particularly in applications involving hybridization. For example, OxoPNA probes may be employed for the detection and functional analysis of nucleic acid molecules, including miRNAs and other non-coding RNAs.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.