Chimeric avian-based screening system containing mammalian grafts
US8324447B2 · kind B2 · utility
8Cited by
4References
7Claims
0Family size
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Key dates
| Filing date | Jun 28, 2005 |
| Grant date | Dec 4, 2012 |
| Priority date | — |
| Expiry date | Aug 20, 2027 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/52
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention relates to animal model systems comprising a chimera between an avian embryo and a mammalian organism. Specifically, chimeric model systems comprising normal, diseased or genetically transformed mammalian cells and tissues transplanted into avian embryos, and uses thereof for in vivo testing of drugs and therapeutic modalities are disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.