Acellular tissue matrices made from alpha-1,3-galactose-deficient tissue

US8324449B2 · kind B2 · utility

Assignee

• LifeCell Corporation · US

Inventors

• David J. McQuillan · Abingdon Reserve, US
• Edward S. Griffey · San Antonio, US
• Herbert Daniel Beniker · San Antonio, US
• Hui Xu · Lo Wu, CN

Key dates

• Filing date: Sep 16, 2010
• Grant date: Dec 4, 2012
• Expiry date: Oct 15, 2030

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N33/6854
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention provides acellular tissue matrices made from collagen-containing tissues of animals genetically modified so as to be deficient in the galactose 1,3-galactose epitope and methods of making and using such acellular tissue matrices.