Patent · US Active

Nanofluidic preconcentration device in an open environment

US8329115B2 · kind B2 · utility

12Cited by
0References
45Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 23, 2009
Grant dateDec 11, 2012
Priority date
Expiry dateMar 27, 2031

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10T137/2224
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

This invention provides a device and methods for increasing the concentration of a charged species in solution, wherein the solution containing the concentrated species is exposed to the environment. Such solution can be formed on a surface or on a tip of a measurement device. The open-environment concentration technique overcomes the disadvantages of in-channel concentration devices, especially by eliminating flow-induced delivery processes that lead to concentration losses. Combined with direct contact dispensing, methods of this invention can be used for various applications such as immunoassay and MALDI-MS.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.