Targeted gene delivery for dendritic cell vaccination
US8329162B2 · kind B2 · utility
9Cited by
28References
17Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 23, 2007 |
| Grant date | Dec 11, 2012 |
| Priority date | — |
| Expiry date | Jul 23, 2027 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods and compositions are provided for delivery of a polynucleotide encoding a gene of interest, typically an antigen, to a dendritic cell (DC). The virus envelope comprises a DC-SIGN specific targeting molecule. The methods and related compositions can be used to treat patients suffering from a wide range of conditions, including infection, such as HIV/AIDS, and various types of cancers.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.