Antibodies inhibiting c-Met dimerization and uses thereof
US8329173B2 · kind B2 · utility
11Cited by
14References
27Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Jul 10, 2008 |
| Grant date | Dec 11, 2012 |
| Priority date | — |
| Expiry date | Oct 20, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/92
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A process for the selection of anti c-Met antibodies capable of inhibiting both ligand-dependent and ligand-independent activation of c-Met, wherein said process is based on the inhibition of the c-Met dimerization. The present invention also concerns such antibodies and compositions comprising antibodies for the preparation of a medicament to treat cancer including diagnosis process and kits.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.