Shell and core dosage form approaching zero-order drug release
US8329215B2 · kind B2 · utility
32Cited by
49References
24Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 8, 2011 |
| Grant date | Dec 11, 2012 |
| Priority date | — |
| Expiry date | Jun 8, 2031 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P31/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Drugs are formulated as oral dosage forms for controlled release in which the release rate limiting portion is a shell surrounding the drug-containing core. The shell releases drug from the core by permitting diffusion of the drug from the core. The shell also motes gastric retention of the dosage form by swelling upon imbibition of gastric fluid to size that is retained in the stomach during the postprandial or fed mode.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.