Chemiluminescence proximity nucleic acid assay
US8329397B2 · kind B2 · utility
3Cited by
19References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 5, 2006 |
| Grant date | Dec 11, 2012 |
| Priority date | — |
| Expiry date | Jun 5, 2026 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6818
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
This invention relates to the detection and quantitation of target nucleic acids in a heterogeneous mixture in a Sample and the methods of use thereof. The detection system includes a chemiluminescent molecule, a chemiluminescent substrate, a dye that is light responsive when intercalated into nucleic acids and nucleic acids. This invention is useful in any application where detection of a specific nucleic acid sequence is desirable, or where the detection of enzymes that modify nucleic acids is desirable such as diagnostics, research uses and industrial applications.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.