Inhibitors of VEGF receptor and HGF receptor signaling
US8329726B2 · kind B2 · utility
0Cited by
16References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 8, 2011 |
| Grant date | Dec 11, 2012 |
| Priority date | — |
| Expiry date | Dec 8, 2031 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to the inhibition of VEGF receptor signaling and HGF receptor signaling. The invention provides compounds of general formula (A)wherein A1 is sulfur, A3 is CH, A2 is CH, D is heterocycle, Z is oxygen, SO0-2 or NR, Ar is phenyl and G is not a ring, and methods for inhibiting VEGF receptor signaling and HGF receptor signaling. The invention also provides compositions and methods for treating cell proliferative diseases and conditions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.