Synthesis and anti-proliferative effect of substituted imidazo[4,5-c]pyridine compounds
US8329728B2 · kind B2 · utility
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21Claims
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Key dates
| Filing date | Dec 20, 2011 |
| Grant date | Dec 11, 2012 |
| Priority date | — |
| Expiry date | Dec 20, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D487/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
This invention provides for compounds, compositions, and methods that involve anti-proliferative and anti-neoplastic activity in cancer cells. In particular, a series of benzimidazole, purine, imidazopyridine, and imidazopyrizine compounds having selected substitution patterns are disclosed, and the activity of various subject compounds is demonstrated. In particular, the disclosure provides for substituted imidazo[4,5-c]pyridine compounds having the general formulatheir salts, pharmaceutical compositions, and methods of treatment using the subject compounds and compositions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.