Detection of specific nitrated markers
US8329874B2 · kind B2 · utility
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1Claims
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Key dates
| Filing date | Aug 30, 2011 |
| Grant date | Dec 11, 2012 |
| Priority date | — |
| Expiry date | Sep 30, 2031 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/173076
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Methods are described for improving the diagnostic possibilities of diseases where oxidative NO-modifications occur, for example inflammatory conditions, cancer, Parkinson's or Alzheimer's disease, and to provide means of monitoring the effects of therapeutical measures taken towards such diseases. The invention enables the detection of disease specific catabolic markers related to oxidative NO-modifications, utilizing an immunoassay comprising antibodies directed against nitrated and non-nitrated epitopes characteristic of a specific protein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.