Optically pure dihydropyrimidine compounds and their uses for the preparation of a medicament for treatment and prevention of viral diseases

US8329902B2 · kind B2 · utility

Assignee

• Beijing Molecule Science and Technology Co., Ltd. · CN

Inventors

• Song Li · Beijing, CN
• Guangqiang Xia · Beijing, CN
• Guoming Zhao · Beijing, CN
• Lili Wang · Beijing, CN
• Zhibing Zheng · Beijing, CN
• Yunde Xie · Beijing, CN
• Wu Zhong · Beijing, CN
• Junhai Xiao · Beijing, CN
• Xingzhou Li · Beijing, CN
• Hao Cui · Beijing, CN

Key dates

• Filing date: Jul 9, 2007
• Grant date: Dec 11, 2012
• Expiry date: Nov 29, 2028

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D239/28
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to an optically pure compound of formula (I) or a pharmaceutically acceptable salt or hydrate thereof, a process for preparing the optically pure compound of formula (I), and use of the optically pure compound of formula (I) or a pharmaceutically acceptable salt or hydrate thereof as a medicament, in particular as a medicament for the treatment and prevention of type B hepatitis.