Derivatives of the NF-κB inducing enzyme, their preparation and use

US8330026B2 · kind B2 · utility

Assignee

• Yeda Research and Development Co. LTD. of Weizmann Institute of Science · IL

Inventors

• David Wallach · Rehovot, IL
• Parameswaran Ramakrishnan · Rehovot, IL
• Taisia Shmushkovich · Rehovot, IL

Key dates

• Filing date: Apr 15, 2003
• Grant date: Dec 11, 2012
• Expiry date: Apr 15, 2023

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2799/022
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to the use of NF-κB inducing kinase (NIK) and related molecules for the modulation of signal activities controlled by cytokines, and some new such molecules.