Field flow fractionator with controllable cross flow along its length
US8333891B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Feb 21, 2012 |
| Grant date | Dec 18, 2012 |
| Priority date | — |
| Expiry date | Feb 21, 2032 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2030/007
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A field flow fractionator to separate particles contained within an injected sample aliquot is described. As required, said fractionator may be used to capture, for subsequent removal, specific predefined classes of such particles. Based upon the cross flow or asymmetric flow field flow fractionators, the fractionator disclosed contains means to vary the applied transverse flows at a plurality of locations along the length of its separating channel. One embodiment utilizes a plurality of separated compartments, each lying below a distinct and corresponding membrane supporting permeable frit segment, are provided individual means to control the localized flow through the membrane section thereabove. A corresponding concentric compartment implementation achieves the same type of compartmentalized cross flow when integrated with a hollow fiber fractionator.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.