Coryneform host-vector systems comprising a chromosomal ALR gene which is attenuated or eliminated and methods of using

US8334126B2 · kind B2 · utility

Assignee

• EVONIK DEGUSSA GMBH · DE

Inventors

• Andreas Tauch · Bielefeld, DE
• Michael Binder · Steinhagen, DE
• Walter Pfefferle · Bodenwerder, DE
• Georg Thierbach · Bielefeld, DE
• Jorn Kalinowski · Bielefeld, DE
• Alfred Puhler · Bielefeld, DE

Key dates

• Filing date: Sep 22, 2011
• Grant date: Dec 18, 2012
• Expiry date: Sep 22, 2031

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12Y501/01001
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The invention relates to an isolated polynucleotide having a polynucleotide sequence which codes for the alr gene, and a host-vector system having a coryneform host bacterium in which the alr gene is present in attenuated form and a vector which carries at least the alr gene according to SEQ ID No 1, and the use of polynucleotides which comprise the sequences according to the invention as hybridization probes.