Method of treating endothelial dysfunction comprising administration of a thrombin peptide derivative

US8334259B2 · kind B2 · utility

Assignees

• The Board of Regents of the University of Texas System · US
• THE TEXAS A&M UNIVERSITY SYSTEM · US

Inventors

• Darrell H. Carney · Dickinson, US
• Barbara Olszewska-Pazdrak · League City, US
• Theresa W. Fossum · College Station, US

Key dates

• Filing date: Sep 21, 2007
• Grant date: Dec 18, 2012
• Expiry date: Jun 7, 2029

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12Y304/21005
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Endothelial dysfunction (ED) is associated with a number of diseases and disorders. Agonists of the non-proteolytically activated thrombin receptor can be used in methods to treat ED or ED-related diseases and disorders.