Pharmaceutical formulation containing gelling agent

US8337888B2 · kind B2 · utility

Assignee

• PURDUE PHARMA L.P. · US

Inventors

• Curtis Wright · Gloucester, US
• Benjamin Oshlack · Boca Raton, US
• Christopher Breder · Bethesda, US

Key dates

• Filing date: Jan 12, 2012
• Grant date: Dec 25, 2012
• Expiry date: Jan 12, 2032

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P25/36
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Disclosed in certain embodiments is a controlled release oral dosage form comprising a therapeutically effective amount of a drug susceptible to abuse together with one or more pharmaceutically acceptable excipients; the dosage form further including a gelling agent in an effective amount to impart a viscosity unsuitable for administration selected from the group consisting of parenteral and nasal administration to a solubilized mixture formed when the dosage form is crushed and mixed with from about 0.5 to about 10 ml of an aqueous liquid; the dosage form providing a therapeutic effect for at least about 12 hours when orally administered to a human patient.