Patent · US Active

Modified mevalonate kinase with reduced feedback inhibition

US8338155B2 · kind B2 · utility

3Cited by

5References

1Claims

0Family size

Assignee

DSM IP ASSETS B.V. · NL

Inventors

Renyuan Bai · Baltimore, US
Markus Wyss · Liestal, CH

Key dates

Filing date	Dec 12, 2005
Grant date	Dec 25, 2012
Priority date	—
Expiry date	Apr 13, 2028

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N9/1205
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The present invention relates to modified mevalonate kinases that are less sensitive to feedback inhibition, and to polynucleotides encoding them. The invention further pertains to vectors comprising these polynucleotides and host cells containing such vectors. The invention provides a process for producing the modified enzyme and for producing isoprenoid compounds using the modified enzymes.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.