Coumarin-amide derivatives and its preparation, said drug composition and its use

US8338401B2 · kind B2 · utility

Assignee

• INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES · CN

Inventors

• Shiping Xu · Wujiang, CN
• Xiaoguang Chen · Beijing, CN
• Song Xu · Beijing, CN
• Lanmin Li · Parla, ES
• Longfei Xie · Groton, US
• Hongyan Li · Kunming, CN
• Yan Li · Tianjin, CN
• Guifang Cheng · Beijing, CN

Key dates

• Filing date: Dec 5, 2003
• Grant date: Dec 25, 2012
• Expiry date: Mar 20, 2025

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D417/12
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to novel coumarin derivatives, their carboxamides, pharmaceutical compositions containing them and their uses as drugs for kidney protection, treating drugs of hypertension, cardio-cerebrovascular diseases, non-insulin dependent diabetes, tumor, pre-cancerous lesion, and edemas.