Indolin-2-ones and aza-indolin-2-ones
US8338422B2 · kind B2 · utility
1Cited by
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19Claims
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Assignee
Inventors
Key dates
| Filing date | Jun 20, 2008 |
| Grant date | Dec 25, 2012 |
| Priority date | — |
| Expiry date | Mar 13, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D487/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to compounds or pharmaceutically-acceptable salts thereof, processes for preparing them, pharmaceutical compositions containing them and their use in therapy. The invention particularly relates to certain indolin-2-ones and aza-indolin-2-ones which possess anti-tumor activity and are accordingly useful in methods of treatment of the human or animal body, in particular such compounds are useful in the treatment of pathological processes which involve an aberrant cellular proliferation, such as tumor growth, rheumatoid arthritis, restenosis and atherosclerosis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.