Inhibitors of IAP

US8338440B2 · kind B2 · utility

Assignee

• Novartis AG · CH

Inventors

• Mark G. Palermo · Rindge, US
• Sushil Sharma · East Hanover, US
• Christopher Sean Straub · Cambridge, US
• Run-Ming David Wang · Cambridge, US
• Leigh Zawel · Bowie, US
• Yanlin Zhang · Somerville, US
• Zhuoliang Chen · Cambridge, US
• Yaping Wang · Cambridge, US
• Fan Yang · Brookline, US
• Wojciech Wrona · Cambridge, US
• Gang Liu · Sugar Land, US
• Mark G. Charest · Montgomery, US
• Feng He · Nanhu, CN

Key dates

• Filing date: Apr 26, 2012
• Grant date: Dec 25, 2012
• Expiry date: Apr 26, 2032

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D487/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Novel compounds that inhibit the binding of the Smac protein to Inhibitor of Apoptosis Proteins (IAPs) of the formula (I).