Snornai-small nucleolar RNA degradation by RNA interference in trypanosomatids
US8338583B2 · kind B2 · utility
38Cited by
1References
2Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Feb 4, 2004 |
| Grant date | Dec 25, 2012 |
| Priority date | — |
| Expiry date | Aug 25, 2026 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2310/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Polynucleotides and a method suitable for downregulation of small nuclear RNA which can be used to treat diseases associated with activity of small nuclear RNA are provided. Specifically, the present invention can be used to downregulate snoRNA molecules or box H/ACA-containing RNA molecules which are involved in diseases such as cancer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.