Pyrrolotriazine derivatives useful for treating cancer through inhibition of aurora kinase

US8338594B2 · kind B2 · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Steven R. Magnuson · South San Francisco, US
• Julie A. Dixon · Bethany, US
• Barton W. Phillips · San Mateo, US
• Uday Khire · Hamden, US
• Lei Wang · Beijing, CN
• Zhonghua Zhang · Derby, US
• Manoj Patel · Berlin, US
• Ellalahewage Sathyajith Kumarasinghe · Harvard, US
• Philip Wickens · Wallingford, US
• Alan Olague · Shelton, US

Key dates

• Filing date: Dec 1, 2006
• Grant date: Dec 25, 2012
• Expiry date: Jun 8, 2028

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D519/00
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

This invention relates to novel compounds and processes for their preparation, methods of treating diseases, particularly Cancer, comprising administering said compounds, and methods of making pharmaceutical compositions for the treatment or prevention of disorders, particularly Cancer.