Quaternary nitrogen heterocyclic compounds for detecting aqueous monosaccharides in physiological fluids
US8338602B2 · kind B2 · utility
19Cited by
15References
5Claims
0Family size
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Key dates
| Filing date | May 18, 2010 |
| Grant date | Dec 25, 2012 |
| Priority date | — |
| Expiry date | Aug 28, 2030 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/193333
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Quaternary nitrogen heterocyclic boronic acid-containing compounds are described, which are sensitive to glucose and fructose, as well as a variety of other physiologically important analytes, such as aqueous chloride and iodide, and a method of using the compounds. Also disclosed is a contact lens doped with the quaternary nitrogen heterocyclic boronic acid-containing compound, and a method of using the doped contact lens to measure the concentration of analyte in tears under physiological conditions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.