Photocrosslinkable oligo(poly (ethylene glycol) fumarate) hydrogels for cell and drug delivery
US8343527B2 · kind B2 · utility
4Cited by
2References
18Claims
0Family size
Inventors
Key dates
| Filing date | Mar 23, 2006 |
| Grant date | Jan 1, 2013 |
| Priority date | — |
| Expiry date | Dec 29, 2027 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB33Y80/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides photocrosslinkable, injectable, biodegradable oligo(poly(ethylene glycol) fumarate) (OPF) hydrogels made from the photopolymerization of an OPF macromer with UV light and a photoinitiator. Hydrogels with varying mechanical properties and water content can be made with changes in macromer and crosslinking agent concentration in a precursor solution. The biodegradable OPF hydrogels can be injected as a fluid into a bodily defect of any shape, may incorporate various therapeutic agents, e.g., cells and/or growth factors, and may be implanted via minimally invasive arthroscopic techniques.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.