Method of treating the surface of a medical device with a biomolecule
US8343567B2 · kind B2 · utility
5Cited by
21References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 9, 2012 |
| Grant date | Jan 1, 2013 |
| Priority date | — |
| Expiry date | Jan 9, 2032 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61M1/1698
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A method of treating the surface of a medical device with a biomolecule comprising the steps of: providing a polyolefin substrate forming a medical device; cleaning the polyolefin substrate; exposing the polyolefin substrate to a reactive gas containing acrylic acid and to plasma energy to yield a plasma-deposited polyacrylic acid coating on the polyolefin substrate; and attaching a biomolecule, such as heparin, to the polyolefin substrate following formation of the plasma-deposited polyacrylic acid coating on the polyolefin substrate.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.